CERVICAL CYTOLOGY FINDINGS IN WOMEN INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS

被引:8
作者
HENRYSTANLEY, MJ
SIMPSON, M
STANLEY, MW
机构
[1] Department of Cytotechnology, College of Health Related Professions
[2] The Department of Pathology, University of Arkansas for the Medical Sciences, Little Rock, Arkansas
[3] The Department of Medicine, Hennepin County Medical Center, Minneapolis, Minnesota
关键词
CYTOLOGY; AIDS; HIV; INFECTION; HPV;
D O I
10.1002/dc.2840090507
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
It has been suggested that immunocompromised, HIV-infected patients are at risk of developing HPV infection and SIL. The well documented role of HPV and SIL in cervical carcinogenesis should lead to frequent, careful evaluation of HIV infected women. Forty-four cervical smears from 23 patients (20 HIV and 3 AIDS) were reviewed. While 11 of the 23 patients produced negative smears, 11 had abnormal cytological findings on at least one occasion. Sixteen smears (36 percent) from 10 patients (43%) showed evidence of HPV and/or SIL. Two smears (two patients) were assigned to the benign epithelial atypia category. (One of these showed keratosis which may indicate HPV infection.) Six smears (three patients) represented either a severe Trichomonas, fungal (Candida sp.), or Herpes infection. Three smears were deemed unsatisfactory for diagnosis due to severe acute inflammation or obscuring blood. Five biopsies were available. In four, histologic findings supported the original cytologic diagnosis. One patient with a negative smear had a biopsy showing condyloma. This study further supports an association of HPV and/or cervical dysplasia with HIV Careful evaluation and follow-up of HIV-infected women is essential. (C) 1993 Wiley-Liss, Inc.
引用
收藏
页码:508 / 509
页数:2
相关论文
共 12 条
[1]  
Henry MJ, Stanley MW, Cruikshank S, Carson L, Association of human immunodeficiency virus‐induced immunosuppression with human papillomavirus infection and cervical intraepithelial neoplasia, Am J Obstet Gynecol, 160, pp. 352-353, (1989)
[2]  
Maiman M, Tarricone N, Vieira J, Suarez J, Serrur I, Boyce JG, Colposcopic evaluation of human immunodeficiency virus‐seropositive women, Obstet Gynecol, 78, pp. 84-88, (1991)
[3]  
Feingold AR, Vermund SH, Burk RD, Cervical cytologic abnormalities and papillomavirus in women infected with human immunodeficiency virus, J Acquir Immune Defic Syndr, 3, pp. 896-903, (1990)
[4]  
Byrne M, Taylor-Robinson D, Harris JR, Cervical dysplasia and HIV infection (letter), Lancet, 1, (1988)
[5]  
Crocchiolo P, Lizioli A, Goisis F, Et al., Cervical dysplasia and HIV infection (letter), Lancet, 1, (1988)
[6]  
Spurrett B, Jones DS, Stewart G, Cervical dysplasia and HIV infection (letter), Lancet, 1, (1988)
[7]  
Bradbeer C, Is infection with HIV a risk factor for cervical intraepithelial neoplasia? (letter), Lancet, 2, (1987)
[8]  
Frazer IH, Medley G, Cropper RM, Brown TC, MacKay IR, Association between anorectal dysplasia, human papillomavirus, and human immunodeficiency virus infection in homosexual men, Lancet, 2, pp. 657-660, (1986)
[9]  
Fineberg SA, Schinella R, Human immunodeficiency virus infection in women: Report of 102 cases, Mod Pathol, 3, pp. 575-580, (1990)
[10]  
Pomerantz RJ, de la Monte SM, Donega SP, Et al., Human immunodeficiency virus (HIV) infection of the uterine cervix, Ann Intern Med, 108, pp. 321-327, (1988)