SUSCEPTIBILITY OF STREPTOCOCCUS-MUTANS AND STREPTOCOCCUS-SOBRINUS TO ANTIMICROBIAL AGENTS AFTER SHORT-TERM ORAL CHLORHEXIDINE TREATMENTS

被引：28

作者：

JARVINEN, H ^{[1
]}

PIENIHAKKINEN, K ^{[1
]}

HUOVINEN, P ^{[1
]}

TENOVUO, J ^{[1
]}

机构：

[1] UNIV TURKU,INST DENT,DEPT CARIOL,TURKU,FINLAND

来源：

EUROPEAN JOURNAL OF ORAL SCIENCES | 1995年 / 103卷 / 01期

关键词：

CHLORHEXIDINE; RESISTANCE; STREPTOCOCCUS MUTANS; STREPTOCOCCUS SOBRINUS;

D O I：

10.1111/j.1600-0722.1995.tb00007.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Effects of three different types of short-term applications (1-3 times during 1 week) of chlorhexidine (1 or 40%) on the susceptibility of 863 clinical isolates of Streptococcus mutans and 53 isolates of Streptococcus sobrinus from 58 subjects were studied. Chlorhexidine-resistant isolates were not found either before or after the treatment. The minimum inhibitory concentrations (MICs) to chlorhexidine sobrinus of all isolates of S. mutans were less than or equal to 1 mu g/ml, and of S. sobrinus less than or equal to 2 mu g/ml. S. mutans and S. sobrinus were also susceptible to ampicillin, penicillin, cefuroxime, and tetracycline. In conclusion, different short-term chlorhexidine regimens do not induce resistance in S. mutans or S. sobrinus and, furthermore, these species have so far retained their susceptibility to common antibiotics.

引用

页码：32 / 35

页数：4

共 31 条

[1] A SIMPLE BIOCHEMICAL SCHEME FOR THE DIFFERENTIATION OF STREPTOCOCCUS-MUTANS AND STREPTOCOCCUS-SOBRINUS [J].