BETA-ENDORPHIN INHIBITS MET-ENKEPHALIN BREAKDOWN BY A BRAIN AMINOPEPTIDASE - STRUCTURE ACTIVITY RELATIONSHIPS

被引：19

作者：

HUI, KS

GRAF, L

LAJTHA, A

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1982年 / 105卷 / 04期

关键词：

D O I：

10.1016/0006-291X(82)90955-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1482 / 1487

页数：6

共 13 条

[1] NH2-TERMINUS OF C-FRAGMENT IS RESISTANT TO ACTION OF AMINOPEPTIDASES [J].

AUSTEN, BM ;

SMYTH, DG .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 76 (02) :477-482

[2] INHIBITION OF ENKEPHALIN-DEGRADING AMINOPEPTIDASE ACTIVITY BY CERTAIN PEPTIDES [J].

BARCLAY, RK ;

PHILLIPPS, MA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 96 (04) :1732-1738

[3] CO-IDENTITY OF BRAIN ANGIOTENSIN CONVERTING ENZYME WITH A MEMBRANE-BOUND DIPEPTIDYL CARBOXYPEPTIDASE INACTIVATING MET - ENKEPHALIN [J].

BENUCK, M ;

MARKS, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1979, 88 (01) :215-221

[4] HYDROLYSIS OF ENKEPHALIN BY CULTURED HUMAN ENDOTHELIAL CELLS AND BY PURIFIED PEPTIDYL DIPEPTIDASE [J].

ERDOS, EG ;

JOHNSON, AR ;

BOYDEN, NT .

BIOCHEMICAL PHARMACOLOGY, 1978, 27 (05) :843-848

[5]

Graf L, 1977, Ann N Y Acad Sci, V297, P63, DOI 10.1111/j.1749-6632.1977.tb41846.x

[6]

GRAF L, 1968, ACTA BIOCHIM BIOPHYS, V3, P175

[7] SOLUBILIZATION AND CHARACTERIZATION OF 2 RAT-BRAIN MEMBRANE-BOUND AMINOPEPTIDASES ACTIVE ON MET-ENKEPHALIN [J].

HERSH, LB .

BIOCHEMISTRY, 1981, 20 (08) :2345-2350

[8] CLEAVAGE OF ENDORPHINS TO DES-TYR ENDORPHINS BY HOMOGENEOUS BOVINE BRAIN AMINOPEPTIDASE [J].

HERSH, LB ;

SMITH, TE ;

MCKELVY, JF .

NATURE, 1980, 286 (5769) :160-162

[9]

HUI KS, 1981, P NATL ACAD SCI US

[10]

KNIGHT M, 1978, J BIOL CHEM, V253, P3843

← 1 2 →