PREPARATION OF A SEMISYNTHETIC ANALOG OF MEVINOLIN AND COMPACTIN

被引：22

作者：

CLIVE, DLJ

WICKENS, PL

DASILVA, GVJ

机构：

[1] Department of Chemistry, University of Alberta, Edmonton

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 17期

关键词：

D O I：

10.1021/jo00122a037

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Enone 5, derived by chemical degradation of compactin (1), was elaborated into the semisynthetic analogue 4, which is an inhibitor of cholesterol biosynthesis in rat liver microsomes.

引用

页码：5532 / 5536

页数：5

共 31 条

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