MICROBIOASSAY OF NYSTATIN WITH A YEAST ELECTRODE

被引：43

作者：

KARUBE, I

MATSUNAGA, T

SUZUKI, S

机构：

[1] Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Midori-ku, Yokohama, 227, Nagatsutacho

来源：

ANALYTICA CHIMICA ACTA | 1979年 / 109卷 / 01期

关键词：

D O I：

10.1016/S0003-2670(01)84224-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Microbioassay of nystatin is achieved with an electrode composed of a yeast membrane and an oxygen electrode, based on the inhibitory action of the antibiotic on the respiration of the yeast. A linear relationship is obtained between the rate of current increase and the potency of nystatin. The minimum measurable nystatin concentration is 0.5 unit ml-1.The assay takes less than l h; the standard deviation is 1.2 unit ml-1 at the 27 USP unit ml-1 level. © 1979.

引用

页码：39 / 44

页数：6

共 11 条

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[8] RAPID-DETERMINATION OF NICOTINIC-ACID BY IMMOBILIZED LACTOBACILLUS-ARABINOSUS
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[9] ELECTROCHEMICAL MICROBIOASSAY OF VITAMIN-B1
MATSUNAGA, T
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[10] RUSSELL AD, 1969, METHOD MICROBIOLOGY, V8, P96

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