DETECTION OF BORDETELLA-PERTUSSIS ASSOCIATED WITH THE ALVEOLAR MACROPHAGES OF CHILDREN WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

被引：67

作者：

BROMBERG, K ^{[1
]}

TANNIS, G ^{[1
]}

STEINER, P ^{[1
]}

机构：

[1] SUNY HLTH SCI CTR, DEPT PEDIAT, BROOKLYN, NY 11203 USA

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 12期

关键词：

D O I：

10.1128/IAI.59.12.4715-4719.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In humans, infection with Bordetella pertussis is considered to be localized to an epithelial surface. However, an intracellular state in cultured cells and in the macrophages of infected animals has been shown. By using indirect immunofluorescence with a monoclonal antibody, it was found that 3 of 20 bronchoalveolar lavage specimens from children with human immunodeficiency virus infection had B. pertussis associated with pulmonary alveolar macrophages. None of the cultures from the patients grew B. pertussis. The B. pertussis appeared to be intracellular.

引用

页码：4715 / 4719

页数：5

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