EFFECTS OF INDOLEAMINES ON SPERM MOTILITY INVITRO

被引：16

作者：

IREZ, TO

SENOL, H

ALAGOZ, M

BASMACIOGULLARI, C

TURAN, F

KURU, D

ERTUNGEALP, E

机构：

[1] University of Istanbul, Cerrahpaşa Medical Faculty, Dept. of Gynaecology and Obstetrics, Andrology Lab, P.K.15, Istanbul

来源：

HUMAN REPRODUCTION | 1992年 / 7卷 / 07期

关键词：

INVITRO; INDOLEAMINES; SPERM MOTILITY;

D O I：

10.1093/oxfordjournals.humrep.a137785

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Indoleamines are products of the pineal gland and are postulated to play an antigonadotrophic role in the reproductive system of mammals. In humans, indoleamines have been localized in tissue fluids such as plasma, serum and cerebrospinal fluid. Because indoleamines exhibit antigonadotrophic properties, the authors examined whether these agents cause inhibitory effects on sperm motility. In this study, time and dose-dependent inhibition of sperm motility by indoleamines was observed. Furthermore, the presence of indoles in incubation medium decreased sperm velocity. These data suggest that the presence of high doses of indoles in reproductive fluids may inhibit sperm motility and velocity.

引用

页码：987 / 990

页数：4

共 27 条

[1]

Aitken R.J., Clarkson J.S., Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques, J. Androl., 9, pp. 367-376, (1988)

[2]

Balemans M.G.M., Age dependent effects of 5-methoxytryptophol and melatonin on tests and comb growth of the white leghorn (Gallus domesticus L.), J. Neural Transm., 33, pp. 178-184, (1972)

[3]

Balemans M.G.M., Veerdonk Van Der F.C.G., Van De Kamer J.C., Influence of 5-methoxytryptophol, a pineal compound on comb growth, ovarian weight, follicular growth and egg production of juvenile and maturing adult white leghorn hens, J. Neural Transm., 41, pp. 37-41, (1971)

[4]

Bardin C.W., Sherins R.J., Cell biology of the testis, Ann. N. Y. Acad. Sci., (1982)

[5]

Blask D.E., Potential sites of action of pineal hormones with the neuroendocrine-reproductive axis, The Pineal Gland, 2, pp. 189-216, (1981)

[6]

Cardinali D.P., Melatonin. A mammalian pineal hormone, Endocr. Rev., 2, pp. 327-346, (1981)

[7]

Cardinali D.P., Freire F., Melatonin effects on brain. Interaction with microtubule protein, inhibition of fast axoplasmic flow and induction of crystalloid and tubular formations in the hypothalamus, Mol. Cell Endocrinol., 2, pp. 317-330, (1975)

[8]

Delvigs P., McLsaac W.M., Taborsky R.G., The metabolism of 5 methoxytryptophol, J. Biol. Chem., 240, pp. 348-351, (1965)

[9]

Elliot F.I., Sherman J.K., Elliot E.J., Sullivan J.J., A photographic method of measuring percentage of progressively motile sperm cells using dark field microscopy, Proceedings VIII International Symposium Zootechnology, Milan, (1973)

[10]

Fawcett D.W., The mammalian spermatozoon, Dev. Biol., 44, pp. 394-436, (1975)

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