MECHANISM OF BIOLUMINESCENCE, CHEMILUMINESCENCE AND ENZYME FUNCTION IN OXIDATION OF FIREFLY LUCIFERIN

被引：150

作者：

MCELROY, WD

SELIGER, HH

WHITE, EH

机构：

[1] Department of Biology, McCollum-Pratt Institute, Department of Chemistry, The Johns Hopkins University, Baltimore, Maryland

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1969年 / 10卷 / 03期

关键词：

D O I：

10.1111/j.1751-1097.1969.tb05676.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abstract— The chemical steps and the products of the bioluminescent and chemiluminescent oxidations of firefly luciferin are elucidated. The colors of firefly bioluminescence can be explained in terms of different ionic excited states and spectral shifts due to changes in molecular environment. Firefly luciferase undergoes conformational changes during catalysis. There are two sites for light production per 100,000 mW. A regulatory mechanism involving dehydro‐luciferin is proposed for control of firefly flashing. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：153 / &

共 41 条

[1] THE FUNCTION OF COENZYME-A IN LUMINESCENCE [J].

AIRTH, RL ;

RHODES, WC ;

MCELROY, WD .

BIOCHIMICA ET BIOPHYSICA ACTA, 1958, 27 (03) :519-532

[2]

BIGGLEY WH, 1966, J GEN PHYSIOL, V50, P1681

[3] EVIDENCE FOR BINDING OF ROSE BENGAL AND ANILINONAPHTHALENESULFONATES AT ACTIVE SITE REGIONS OF LIVER ALCOHOL DEHYDROGENASE [J].

BRAND, L ;

GOHLKE, JR ;

RAO, DS .

BIOCHEMISTRY, 1967, 6 (11) :3510-+

[4] ROLE OF SULFHYDRYL GROUPS IN FIREFLY LUCIFERASE [J].

DELUCA, M ;

WIRTZ, GW ;

MCELROY, WD .

BIOCHEMISTRY, 1964, 3 (07) :935-&

[5] CONFORMATIONAL CHANGES OF LUCIFERASE DURING CATALYSES TRITIUM-HYDROGEN EXCHANGE AND OPTICAL ROTATION STUDIES [J].

DELUCA, M ;

MARSH, M .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1967, 121 (01) :233-&

[6] HYDROPHOBIC NATURE OF ACTIVE SITE OF FIREFLY LUCIFERASE [J].

DELUCA, M .

BIOCHEMISTRY, 1969, 8 (01) :160-&

[7] HYDROLASE PROPERTIES OF FIREFLY LUCIFERASE [J].

DELUCA, M ;

MCELROY, WD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1965, 18 (5-6) :836-&

[8] FLUORESCENT PROBES AND CONFORMATION OF PROTEINS [J].

EDELMAN, GM ;

MCCLURE, WO .

ACCOUNTS OF CHEMICAL RESEARCH, 1968, 1 (03) :65-&

[9] CHEMILUMINESCENCE OF FIREFLY LUCIFERIN . A MODEL FOR BIOLUMINESCENT REACTION AND IDENTIFICATTION OF PRODUCT EXCITED STATE [J].

HOPKINS, TA ;

SELIGER, HH ;

WHITE, EH ;

CASS, MW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1967, 89 (26) :7148-&

[10]

HOPKINS TA, 1968, FED PROC, V27, P640

← 1 2 3 4 5 →