RECONSTITUTION OF APOMYOGLOBIN WITH BILE-PIGMENTS

被引：13

作者：

FALK, H

MARKO, H

MULLER, N

SCHMITZBERGER, W

STUMPE, H

机构：

[1] Institut für Chemie, Johannes-Kepler-Universität, Linz

来源：

MONATSHEFTE FUR CHEMIE | 1990年 / 121卷 / 11期

关键词：

2,3-Dihydrobilindiones; Absorption Spectra; Apomyoglobin; Bilindiones; Circular Dichroism; Formation Constants; Protein - Bile Pigment Complexes;

D O I：

10.1007/BF00808953

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Apomyoglobin was reconstituted with bile pigments of the verdinoid, 2,3-dihydroverdinoid, pterobilinoid, and violinoid type. Absorption and circular dichroism data as well as formation constants of the complexes were measured. From these results it was concluded that chromophore binding and induced chirality of these pigments are mainly governed by a lipophilic region opposite to the propionic side chain(s) and the asymmetric position of the hydrogen bonding acceptors of the propionic acid side chain(s) at the entrance of the protein pocket. © 1990 Springer-Verlag.

引用

页码：893 / 901

页数：9

共 19 条

[1] COMPLEXES OF BILIRUBIN WITH PROTEINS [J].