EFFECT OF THE SUBSTITUENTS ON THE DIASTEREOSELECTIVITY IN THE REDUCTION OF CYCLOPROPYL KETONES

被引：13

作者：

DELANGHE, PHM ^{[1
]}

LAUTENS, M ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT CHEM,TORONTO,ON M5S 1A1,CANADA

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 51期

关键词：

D O I：

10.1016/0040-4039(94)88499-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reduction of several cyclopropyl ketones with hydride reagents was studied. High diastereoselectivities (15 to 20 : 1) were obtained with cis-cyclopropyl ketones, while virtually no facial selectivity was observed for the trans-analogues.

引用

页码：9513 / 9516

页数：4

共 16 条

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