CARNITINE-ACETYL-TRANSFERASE IN HUMAN SPERMATOZOA AND SEMINAL PLASMA DETERMINED BY A SENSITIVE RADIOISOTOPE METHOD - POSSIBLE EXTRACELLULAR FUNCTION

被引：9

作者：

BOHMER, T ^{[1
]}

JOHANSEN, L ^{[1
]}

KJEKSHUS, E ^{[1
]}

机构：

[1] UNIV OSLO,RIKSHOP,DEPT OBSTET & GYNECOL,OSLO,NORWAY

来源：

INTERNATIONAL JOURNAL OF ANDROLOGY | 1978年 / 1卷 / 03期

关键词：

acetylcarnitine uptake; carnitine‐acetyl‐transferase; ejaculate; human spermatozoa; seminal plasma; short‐chain fatty acid activation;

D O I：

10.1111/j.1365-2605.1978.tb00598.x

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

The activity of carnitine acetyl‐transferase (CAT) (E. C. 2. 3. 1. 7) has been determined in human seminal plasma and spermatozoa by a sensitive radioisotopic assay. 45 to 75 per cent of total CAT activity in the ejaculate is located in the seminal plasma, but the concentration of CAT (nmol [14C] acetylcarnitine formed per min per μl) is 30–120 fold higher in spermatozoa than in seminal plasma. Enzymes activating short‐chain fatty acids, e. g. acetate and propionate, are present in seminal plasma. Radiolabelled acetylcarnitine is not taken up by the human ejaculated spermatozoa. Copyright © 1978, Wiley Blackwell. All rights reserved

引用

页码：262 / 269

页数：8

共 14 条

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