IMPORTANCE OF HEPATIC NEOPLASMS IN LOWER VERTEBRATE ANIMALS AS A TOOL IN CANCER-RESEARCH

被引：27

作者：

ISHIKAWA, T

TAKAYAMA, S

机构：

[1] Department of Experimental Pathology, Cancer Institute, Tokyo

来源：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH | 1979年 / 5卷 / 2-3期

关键词：

D O I：

10.1080/15287397909529765

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Hepatic tumors were induced in medakas (Oryzias latipes) by the addition of diethylnitrosamine (DEN) to their aquarium water. Medakas are useful for study because they are highly susceptible to the carcinogenic effect of DEN and the time for tumor induction is relatively short. Tumors had a histological pattern similar to that of mammalian hepatic tumors. The medaka seems to be susceptible to watersoluble carcinogens. © 1979 by Hemisphere Publishing Corporation.

引用

页码：537 / 550

页数：14

共 30 条

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