NEW PARAHERQUAMIDE ANTIBIOTICS WITH ANTHELMINTIC ACTIVITY

被引:83
作者
BLANCHFLOWER, SE
BANKS, RM
EVERETT, JR
MANGER, BR
READING, C
机构
[1] SMITHKLINE BEECHAM ANIM HLTH,WALTON OAKS,TADWORTH KT20 7NT,SURREY,ENGLAND
[2] SMITHKLINE BEECHAM PHARMACEUT,CHEMOTHERAPEUT RES CTR,BETCHWORTH RH3 7AJ,SURREY,ENGLAND
关键词
D O I
10.7164/antibiotics.44.492
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Paraherquamide (1) an anthelmintic alkaloid, was isolated from a species of Penicillium along with three novel analogues 2, 3 and 4. Anthelmintic activity at least equal to that of paraherquamide is described for the 14-de-hydroxy compound, VM 54159 (4).
引用
收藏
页码:492 / 497
页数:6
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