RENAL EXCRETION OF URATE BY HYPERURICAEMIC-HYPERLIPIDEMIC PATIENTS

被引：6

作者：

ESTEVEZ, EC

MADUENO, FJT

RUIZ, AG

BARBUDO, JA

PRIEGO, MP

GUIJO, PS

机构：

[1] Unidad Docente de Patología General, Departamento de Medicina, Universidad de Córdoba

[2] Sección de Reumatologia, Hospital Universitario, Córdoba

[3] Departamento de Bioquímica, Biología Molecular y Fisiología, Universidad de Córdoba, Córdoba

来源：

CLINICAL RHEUMATOLOGY | 1992年 / 11卷 / 04期

关键词：

HYPERURICEMIA; HYPERLIPIDEMIA; RENAL URATE EXCRETION;

D O I：

10.1007/BF02283105

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We studied the renal urate excretory function in two groups of hyperuricaemic male patients composed of individuals with associated hyperlipidemia and hyperuricaemic-normolipidemic individuals, respectively. Both the hyperlipidemia and the hyperuricaemia were primary inasmuch as none of the patients studied was obese or had an above-normal alcohol intake or blood hypertension. The results obtained show that hyperuricaemic-hyperlipidemic patients have higher serum levels of uric acid and poorer urate excretion as reflected in smaller clearance and fractioned excretion of the metabolite than hyperuricaemic-normolipidemic patients. This, in turn, suggests the occurrence of differences in the extent of the urate handling anomalies between the two groups of patients.

引用

页码：498 / 501

页数：4

共 17 条

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