AGE DEPENDENCE OF 5-METHOXYTRYPTAMINE-INDUCED HINDLIMB SCRATCHING IN RATS

被引：5

作者：

BERENDSEN, HHG

BROEKKAMP, CLE

机构：

[1] CNS Pharmacology Department, Organon International B.V., 5340 BH Oss

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1991年 / 199卷 / 01期

关键词：

HINDLIMB SCRATCHING; 5-HT1D RECEPTORS; ONTOGENY; BEHAVIOR; (RAT);

D O I：

10.1016/0014-2999(91)90643-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The influence of age on hindlimb scratching induced in rats by the serotonin agonist, 5-methoxytryptamine (5-MeOT), was studied. The 5-MeOT-induced scratching was strongest in 30-day-old rats and least in 90-day-old rats. Sex hormones do not play a role in these differences since treatment of young male rats with testosterone propionate did not change the scratching response. The same age dependence was found for female rats as for males.

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页码：107 / 109

页数：3

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