ATP VERSUS PYROPHOSPHATE - GLYCOLYSIS REVISITED IN PARASITIC PROTISTS

被引：97

作者：

MERTENS, E ^{[1
]}

机构：

[1] INT INST CELLULAR & MOLEC PATHOL,B-1200 BRUSSELS,BELGIUM

来源：

PARASITOLOGY TODAY | 1993年 / 9卷 / 04期

关键词：

D O I：

10.1016/0169-4758(93)90169-G

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

It is generally assumed that glycolysis is remarkably similar among all organisms, prokaryotic and eukaryotic. This view has been extended to protists. However, there is growing evidence that significant deviations from conventional glycolysis occur in protists. Very different species, some parasitic, rely on peculiar enzymes that use pyrophosphate as substrate. In this review, Emmanuel Mertens describes such unusual pyrophosphate metabolism in parasitic protists.

引用

页码：122 / 126

页数：5

共 43 条

[1]

Benziman M, 1975, Methods Enzymol, V42, P192

[2] LIGHT DARK MODULATION OF LEAF PYRUVATE, P(I) DIKINASE [J].

BURNELL, JN ;

HATCH, MD .

TRENDS IN BIOCHEMICAL SCIENCES, 1985, 10 (07) :288-291

[3] METABOLIC DIFFERENCES BETWEEN METRONIDAZOLE RESISTANT AND SUSCEPTIBLE STRAINS OF TRITRICHOMONAS-FOETUS [J].

CERKASOVOVA, AP ;

CERKASOV, J ;

KULDA, J .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1984, 11 (APR) :105-118

[4] ALANINE IS A MAJOR END PRODUCT OF METABOLISM BY GIARDIA-LAMBLIA - A PROTON NUCLEAR MAGNETIC-RESONANCE STUDY [J].

EDWARDS, MR ;

GILROY, FV ;

JIMENEZ, BM ;

OSULLIVAN, WJ .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 37 (01) :19-26

[5]

Fulton J. D., 1960, Experimental Parasitology, V9, P293, DOI 10.1016/0014-4894(60)90037-0

[6] IDENTIFICATION, PURIFICATION AND SEPARATION OF DIFFERENT ISOZYMES OF NADP-SPECIFIC MALIC ENZYME FROM TRITRICHOMONAS-FETUS [J].

HRDY, I ;

MERTENS, E ;

VANSCHAFTINGEN, E .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1993, 57 (02) :253-260

[7]

HRDY I, IN PRESS EXP PARASIT

[8] BIOCHEMISTRY AND METABOLISM OF GIARDIA [J].

JARROLL, EL ;

MANNING, P ;

BERRADA, A ;

HARE, D ;

LINDMARK, DG .

JOURNAL OF PROTOZOOLOGY, 1989, 36 (02) :190-197

[9] ACYL PYROPHOSPHATES - ACTIVATED ANALOGS OF PYROPHOSPHATE MONOESTERS PERMITTING NEW DESIGNS FOR INACTIVATION OF TARGETED ENZYMES [J].

KLUGER, R ;

HUANG, Z .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (13) :5124-5125

[10] MOLECULAR COMPARISON OF PYROPHOSPHATE-DEPENDENT AND ATP-DEPENDENT FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASES FROM POTATO-TUBER [J].

KRUGER, NJ ;

HAMMOND, JBW .

PLANT PHYSIOLOGY, 1988, 86 (03) :645-648

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