ENANTIOMER SEPARATIONS BY SUPERCRITICAL-FLUID CHROMATOGRAPHY ON A CHIRAL STATIONARY-PHASE PHYSICALLY ANCHORED TO POROUS GRAPHITIC CARBON

被引：19

作者：

WILKINS, SM

TAYLOR, DR

SMITH, RJ

机构：

[1] UNIV MANCHESTER,INST SCI & TECHNOL,DEPT CHEM,MANCHESTER M60 1QD,LANCS,ENGLAND

[2] SMITHKLINE BEECHAM PHARMACEUT,HARLOW CM19 5AD,ESSEX,ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY A | 1995年 / 697卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(94)00787-A

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A chiral anthrylamine derivative was prepared and adsorbed on the surface of pre-packed porous graphitic carbon, and was evaluated as a chiral stationary phase in packed-column supercritical (and sub-critical) fluid chromatography. It successfully separated the enantiomers of two commercial anti-inflammatory agents and also a series of racemic tropic acid derivatives.

引用

页码：587 / 590

页数：4

共 7 条

[1]

BRIDGER GJ, 1987, THESIS UMIST MANCHES

[2] RESOLUTION OF CHIRAL COMPOUNDS BY HPLC USING MOBILE PHASE ADDITIVES AND A POROUS GRAPHITIC CARBON STATIONARY PHASE [J].