SYNTHESIS OF RACEMIC THREO- AND ERYTHRO-BETA-HYDROXYLYSINES

被引：8

作者：

STAMMER, CH

WEBB, RG

机构：

[1] Department of Chemistry, University of Georgia, Athens

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 08期

关键词：

D O I：

10.1021/jo01260a014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of both threo- and enthro-β-hydroxy-DL-lysines from an erythro-β-methoxy-β-bromohexanoic acid derivative has been accomplished. Amination of this acid in ammonium hydroxide proceeded with retention while treatment with sodium azide proceeded with inversion of the configuration at the α-carbon atom giving intermediates convertible into the two diastereomeric amino acids. © 1969, American Chemical Society. All rights reserved.

引用

页码：2306 / &

共 40 条

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