IMPLICATIONS OF INTERSCAPULAR BROWN ADIPOSE-TISSUE REMOVAL AND SUCROSE OVERFEEDING ON THE SYMPATHOADRENAL ACTIVITY AND METABOLIC RESPONSES

被引：4

作者：

DAVIDOVIC, V ^{[1
]}

GLISIC, S ^{[1
]}

DEDOVIC, N ^{[1
]}

机构：

[1] INST BIOL RES, DEPT ENDOCRINOL & METAB, BELGRADE, YUGOSLAVIA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY | 1990年 / 97卷 / 02期

关键词：

D O I：

10.1016/0300-9629(90)90174-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. The influence of sucrose overfeeding on the sympatho-adrenal (SA) and metabolic responses was studied in sham-operated (SHAM) rats and in those with interscapular brown adipose tissue (IBAT) removed. 2. 2. Sucrose feeding significantly increased the SA activity, mobilized the free fatty acids (FFA), but did not change glucose homeostasis in sham-operated rats. 3. 3. IBAT removal in control rats fed a stock diet modified the SA activity whereas the levels of both blood glucose and serum FFA were unchanged. 4. 4. However, sucrose in rats void of IBAT potentiated the activity of sympathetic nervous system only and prevented the FFA rise, which is seen in sham-operated sucrose fed rats indicating that the enhanced level of serum FFA in these animals principally originated from the IBAT. © 1990.

引用

页码：217 / 219

页数：3

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