SERPENTINE SUPRAVENOUS HYPERPIGMENTATION INDUCED BY THE NITROSOUREA FOTEMUSTINE

被引：12

作者：

CLAUDY, AL

LEVIGNE, V

BOUCHERON, S

机构：

[1] UNIV HOSP ST PRIEST EN JAREZ,HOP NORD,DEPT DERMATOL,ST PRIEST JAREZ,FRANCE

[2] UNIV HOSP ST PRIEST EN JAREZ,HOP NORD,DEPT PATHOL,ST PRIEST JAREZ,FRANCE

来源：

DERMATOLOGY | 1992年 / 184卷 / 01期

关键词：

PIGMENTATION; HYPERPIGMENTATION; NITROSOUREA; CUTANEOUS DRUG ERUPTION; FOTEMUSTINE;

D O I：

10.1159/000247504

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Two cases of serpentine supravenous hyperpigmentation developing in the area of fotemustine infusions are reported. Histological features showed an increased melanin synthesis and the presence of melanophages without focal degeneration of basal cells or dermal inflammatory infiltrate. Perls' strain was negative. Hypotheses concerning the mechanisms of increased melanin synthesis over the veins are discussed.

引用

页码：70 / 72

页数：3

共 6 条

[1] CUTANEOUS COMPLICATIONS OF CHEMOTHERAPEUTIC-AGENTS [J].