CHARACTERISTICS OF SEROGROUP-A NEISSERIA-MENINGITIDIS STRAINS ISOLATED IN THE CENTRAL-AFRICAN-REPUBLIC IN FEBRUARY 1992

被引：11

作者：

GUIBOURDENCHE, M

CAUGANT, DA

HERVE, V

DEBONNE, JM

LANCKRIET, C

MERLIN, M

MATHIOT, C

ROUNGOU, JB

MARTET, G

RIOU, JY

机构：

[1] INST PASTEUR,CTR NATL REFERENCE MENINGOCOQUES & NEISSERIA APPARANTEES,F-75724 PARIS 15,FRANCE

[2] NATL INST PUBL HLTH,WHO,COLLABORATING CTR REFERENCE & RES MENINGOCOCCI,N-0462 OSLO 4,NORWAY

[3] INST PASTEUR,BANGUI,CENT AFR REPUBL

[4] HOP INSTRUCT ARMEES LAVERAN,SERV PATHOL INFECT,F-13000 MARSEILLE,FRANCE

[5] HOP INSTRUCT ARMEES LAVERAN,BIOL MED LAB,F-13000 MARSEILLE,FRANCE

[6] CNHU,CTR PEDIAT,BANGUI,CENT AFR REPUBL

[7] SERV SANTE ARMEES,INST MED TROP,F-1300 MARSEILLE,FRANCE

[8] DIRECT MED PREVENT & GRANDES ENDEMIES,BANGUI,CENT AFR REPUBL

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1994年 / 13卷 / 02期

关键词：

D O I：

10.1007/BF01982194

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A severe epidemic of serogroup A meningococcus meningitis occurred in the northwest Central African Republic from January to March 1992. Strains from 24 patients were characterized using serotyping, testing of susceptibility to antibiotics, and multilocus enzyme electrophoresis. In 23 of the 24 patients the causal strain was found to be 4:P1.9/clone III-1. These results indicate that such strains continue to spread in Africa and have taken hold in areas outside the ''meningitis belt.'' This may be a consequence of changing climatic conditions.

引用

页码：174 / 177

页数：4

共 14 条

[1] A COMPARISON OF THE VARIABLE ANTIGENS EXPRESSED BY CLONE-IV-1 AND SUBGROUP-III OF NEISSERIA-MENINGITIDIS SEROGROUP-A [J].