EFFECT OF VAGOTOMY OR ATROPINE ON CANINE PANCREATIC RESPONSE TO SECRETIN AND PANCREOZYMIN

被引:79
作者
HENRIKSE.FW
机构
[1] Institute of Experimental Research in Surgery, University of Copenhagen, Copenhagen
[2] Institute of Experimental Research in Surgery, Copenhagen Ö, 71
关键词
Atropine; Pancreas; Pancreatic juice; Pancreozymin; Secretin; Vagotomy;
D O I
10.3109/00365526909179921
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
In 7 dogs with chronic, duodenal Thomas fistulas and gastrostomies, vagotomy had no effect on the basal secretion, and also failed to change the response to exogenous hormonal stimulation. Atropine had a pronounced depressing effect on the basal secretion of fluid. Also the protein secretion in response to secretin was reduced. The secretion of fluid and bicarbonate in response to isolated stimulation with pancreozymin increased after atropine, whereas the secretin-stimulated secretion remained unchanged. The findings indicate the existence of local cholinergic mechanisms. © 1969 Informa UK Ltd.
引用
收藏
页码:137 / &
相关论文
共 22 条
  • [1] ANNIS D, 1951, P SOC EXP BIOL MED, V77, P383
  • [2] ANNIS D, 1951, GASTROENTEROLOGY, V17, P560
  • [3] POTENTIATION OF SCRETIN STIMULATION OF PANCREAS
    BROWN, JC
    HARPER, AA
    SCRATCHERD, T
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1967, 190 (03): : 519 - +
  • [4] DEREUCK AVS, 1962, EXOCRINE PANCREAS ED, P208
  • [5] DREILING DA, 1952, GASTROENTEROLOGY, V20, P578
  • [6] DREILING DA, 1960, AMER J DIG DIS, V5, P693
  • [7] FISHER RA, 1958, STATISTICAL METHODS, P99
  • [8] GREENLEE HB, 1959, ARCH SURG-CHICAGO, V79, P1004
  • [9] GROSSMAN MI, 1962, EXOCRINE PANCREAS, P208
  • [10] INTERACTION OF SECRETIN AND PANCREOZYMIN ON EXTERNAL PANCREATIC SECRETION IN DOGS
    HENRIKSEN, FW
    WORNING, H
    [J]. ACTA PHYSIOLOGICA SCANDINAVICA, 1967, 70 (02): : 241 - +