FEVER PATTERNS - THEIR LACK OF CLINICAL SIGNIFICANCE

Fever patterns were studied prospectively in 200 consecutive patients referred for infectious disease consultation and retrospectively in 204 patients with selected infectious or non-infectious diseases. Most patients had remittent or intermittent fever which, when due to infection, usually followed diurnal variation. Hectic fever occurred less commonly but was observed in patients with all categories of infectious or non-infectious diseases. Although hectic fevers were seen more frequently in patients who had documented bacteremia, there were many non-bacteremic subjects with and others without this pattern who had bacteremia. Sustained fever nearly always occurred in patients with gram-negative pneumonia or CNS damage, although some patients with these diseases also had other patterns. With the possible exception of sustained fever in gram-negative penumonia or CNS damage, the fever pattern may not be helpful diagnostically.