STEREOSPECIFIC 1,2-ARYL MIGRATION IN 2-HYDROXY ALKYL ARYL ACETALS WITH PPH3/CCL4 - SYNTHESES OF OPTICALLY-ACTIVE IBUPROFEN AND NAPROXEN

被引：9

作者：

SONAWANE, HR

NANJUNDIAH, BS

KULKARNI, DG

AHUJA, JR

机构：

[1] National Chemical Laboratory, Pune

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(00)80045-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Treatment of 2-hydroxy acetals (R)-(-)-1 and (R)-(-)-3 with PPh3 and CCl4 resulted in a stereospecific 1,2-aryl migration leading to the asymmetric synthesis of (R)-(-)-2 and (R)-(-)-4 respectively.

引用

页码：251 / 252

页数：2

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