SALTATION AND STASIS - A MODEL OF HUMAN GROWTH

被引:226
作者
LAMPL, M
VELDHUIS, JD
JOHNSON, ML
机构
[1] UNIV VIRGINIA, HLTH SCI CTR, NATL SCI FDN, CTR BIOL TIMING, CHARLOTTESVILLE, VA 22908 USA
[2] UNIV VIRGINIA, HLTH SCI CTR, DEPT INTERNAL MED, DIV ENDOCRINOL & METAB, CHARLOTTESVILLE, VA 22908 USA
[3] UNIV VIRGINIA, HLTH SCI CTR, DEPT PHARMACOL, CHARLOTTESVILLE, VA 22908 USA
关键词
D O I
10.1126/science.1439787
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Human growth has been viewed as a continuous process characterized by changing velocity with age. Serial length measurements of normal infants were assessed weekly (n = 10), semiweekly (n = 18), and daily (n = 3) (19 females and 12 males) during their first 21 months. Data show that growth in length occurs by discontinuous, aperiodic saltatory spurts. These bursts were 0.5 to 2.5 centimeters in amplitude during intervals separated by no measurable growth (2 to 63 days duration). These data suggest that 90 to 95 percent of normal development during infancy is growth-free and length accretion is a distinctly saltatory process of incremental bursts punctuating background stasis.
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页码:801 / 803
页数:3
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