RENAL VENOUS ERYTHROPOIETIN CONCENTRATIONS IN HYPERTENSIVE PATIENTS WITH UNILATERAL RENAL-DISEASE

被引：12

作者：

LABEEUW, M ^{[1
]}

PROST, NF ^{[1
]}

DAOUD, S ^{[1
]}

LAPRA, C ^{[1
]}

ZECH, P ^{[1
]}

POZET, N ^{[1
]}

机构：

[1] E HERRIOT HOSP,RENAL FUNCT UNIT,LYON,FRANCE

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 1992年 / 7卷 / 12期

关键词：

ERYTHROPOIETIN; SECRETION; RENAL VEIN; SECONDARY HYPERTENSION; UNILATERAL RENAL DISEASE;

D O I：

10.1093/ndt/7.12.1190

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

In 24 hypertensive patients with unilateral renal disease, the erythropoeitin (Epo) concentration ratio in the renal veins was compared with the renin ratio. Seven patients showed moderately elevated peripheral Epo values. Epo and plasma renin activity were significantly positively correlated both in peripheral and renal veins. This suggests that the reduction of renal blood flow was a common, but not unique, stimulating factor of Epo and renin secretion. Epo ratio appeared insensitive since it was greater than 1.5 in only 30% of patients with a renin ratio >2. Our results indicate that the Epo concentration ratio in renal veins cannot be proposed as a substitute for the currently used renin ratio.

引用

页码：1190 / 1193

页数：4

共 9 条

[1] MULTIPLE SITE ESTIMATES OF ERYTHROPOIETIN AND RENIN IN POLYCYTHEMIC KIDNEY-TRANSPLANT PATIENTS [J].