NEW INSIGHTS INTO THE MAN-MOUSE COMPARATIVE MAP OF THE X-CHROMOSOME

被引：45

作者：

BLAIR, HJ ^{[1
]}

REED, V ^{[1
]}

LAVAL, SH ^{[1
]}

BOYD, Y ^{[1
]}

机构：

[1] MRC,RADIOBIOL UNIT,DIV GENET,DIDCOT OX11 ORD,OXON,ENGLAND

来源：

GENOMICS | 1994年 / 19卷 / 02期

关键词：

D O I：

10.1006/geno.1994.1050

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two conserved loci, DXHX674h and DXHX679h, which map to Xp11.22--Xp11.21 on the human X chromosome short arm, have been positioned between the loci for proteolipid protein (Pip) and the Ela subunit of pyruvate dehydrogenase (Pdha1) in the distal region of the mouse X chromosome using Mus musculus x Mus spretus interspecific backcrosses. These data, together with previous comparative mapping studies on another conserved locus (DXF34) and the locus that encodes the erythroid transcription factor (GATA1), reveal that loci that map to the proximal region of the human X chromosome short arm lie in four different regions of the mouse X chromosome and that the human and mouse X chromosomes contain a minimum of eight conserved segments. (C) 1994 Academic Press, Inc.

引用

页码：215 / 220

页数：6

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