EFFECT OF CHRONIC PROTEIN-MALNUTRITION ON EXPERIMENTALLY INDUCED SEIZURES IN RAT

被引:26
作者
FORBES, WB
STERN, WC
TRACY, CA
RESNICK, O
MORGANE, PJ
机构
[1] Worcester Foundation for Experimental Biology, Shrewsbury
关键词
D O I
10.1016/0014-4886(78)90069-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Rats malnourished at various stages of development by feeding them a low protein diet were tested at adulthood for susceptibility to motor seizures induced by pentylenetetrazol (PTZ), electroconvulsive shock (ECS), or amygdaloid kindling. Compared to control animals, malnourished rats were more sensitive to ECS, less susceptible to kindled motor seizures, and did not differ in sensitivity to PTZ. We conclude that malnutrition during development does not exert a uniform effect on all classes of seizure phenomena. © 1978.
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页码:475 / 481
页数:7
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