ISOLATION OF RADIOACTIVE AMINO ACIDS AND DERIVATIVES FROM PERIPHERAL NERVE

被引：3

作者：

CASTON, JD

SINGER, M

机构：

[1] Department of Anatomy, School of Medicine, Case Western Reserve University, Cleveland

[2] Developmental Biology Center, Case Western Reserve University, Cleveland

来源：

EXPERIMENTAL NEUROLOGY | 1969年 / 25卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0014-4886(69)90138-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The small molecule fraction isolated from peripheral nerves has been partially characterized. Five to 24 hours after radioactive amino acids were presented to the animal as much as 90% of the isotope in the nerve was recovered in the small molecule fraction. The radioactivity in this fraction was found to be distributed between the original amino acid and several of its metabolic derivatives. The results show that peripheral nerve maintains a large pool of amino acids and suggest that the tissue contains enzymes necessary for the degradation and interconversion of amino acids. © 1969.

引用

页码：438 / &