ENZYMATIC N-ACETYLATION OF TRYPTAMINE BY BRAIN HOMOGENATES OF LOCUSTA-MIGRATORIA BEFORE AND AFTER INTOXICATION BY CHLORDIMEFORM OR LINDANE

被引:12
作者
ALLAIS, JP [1 ]
GRIPOIS, D [1 ]
MORETEAU, B [1 ]
RAMADE, F [1 ]
机构
[1] UNIV PARIS 11,ENDOCRINOL LAB,F-91405 ORSAY,FRANCE
来源
EXPERIENTIA | 1979年 / 35卷 / 10期
关键词
D O I
10.1007/BF01964006
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Brain homogenates of Locusta migratoria are found to possess enzyme capable of catalyzing the N-acetylation of tryptamine. A main product of the enzymatic reaction is isolated and identified as N-acetyltryptamine by chromatography analyse. Both insecticides, chlordimeform and lindane, inhibit enzyme activity. A direct correlation between the degree of intoxication and acetylation of tryptamine is described. © 1979 Birkhäuser Verlag.
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页码:1357 / 1359
页数:3
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