HIGHLY EFFICIENT AND STEREOCONTROLLED SYNTHETIC ROUTE TO ENANTIOPURE ACC DERIVATIVES - SYNTHESIS OF (+)-N-BENZYLOXYCARBONYL-GAMMA,SIGMA-DEHYDRO-ALLO-CORONAMIC ACID METHYL-ESTER

被引：22

作者：

JIMENEZ, JM ^{[1
]}

CASAS, R ^{[1
]}

ORTUNO, RM ^{[1
]}

机构：

[1] UNIV AUTONOMA BARCELONA,DEPT QUIM,E-08193 BARCELONA,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)78226-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly diastereoselective cyclopropanation of a chiral alpha,beta-dehydroamino acid derivative, obtained from D-mannitol, leads to a single isomer which has been transformed into the title compound in 65% overall yield. This product can be a useful intermediate in the synthesis of enantiopure ACC derivatives.

引用

页码：5945 / 5948

页数：4

共 15 条

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