SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 6'-N-ALKYL DERIVATIVES OF 1-N-[(S)-4-AMINO-2-HYDROXYBUTYRYL]-KANAMYCIN

被引：7

作者：

UMEZAWA, H ^{[1
]}

IINUMA, K ^{[1
]}

KONDO, S ^{[1
]}

MAEDA, K ^{[1
]}

机构：

[1] INST MICROBIAL CHEM,SHINAGAWA,TOKYO,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1975年 / 28卷 / 06期

关键词：

D O I：

10.7164/antibiotics.28.483

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：483 / 485

页数：3

共 6 条

[1]

KAWABE H, IN PRESS

[2] BB-K8, - NEW SEMISYNTHETIC AMINOGLYCOSIDE ANTIBIOTIC [J].

KAWAGUCHI, H ;

NAITO, T ;

NAKAGAWA, S ;

FUJISAWA, K .

JOURNAL OF ANTIBIOTICS, 1972, 25 (12) :695-708

[3] SYNTHESES OF 1-N-[(S)-4-AMINO-2-HYDROXYBUTYRYL]-KANAMYCIN B AND -3', 4'-DIDEOXYKANAMYCIN B ACTIVE AGAINST KANAMYCIN-RESISTANT BACTERIA [J].

KONDO, S ;

IINUMA, K ;

YAMAMOTO, H ;

MAEDA, K ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1973, 26 (07) :412-415

[4] SYNTHESES OF ISOSERYL DERIVATIVES OF KANAMYCINS AND THEIR ANTIBACTERIAL ACTIVITIES [J].

KONDO, S ;

IINUMA, K ;

HAMADA, M ;

MAEDA, K ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1974, 27 (01) :90-93

[5] SYNTHESES OF 6'-N-METHYL-KANAMYCIN AND 3',4'-DIDEOXY-6'-N-METHYLKANAMYCIN B ACTIVE AGAINST RESISTANT STRAINS HAVING 6'-N-ACETYLATING ENZYMES [J].

UMEZAWA, H ;

NISHIMURA, Y ;

TSUCHIYA, T ;

UMEZAWA, S .

JOURNAL OF ANTIBIOTICS, 1972, 25 (12) :743-745

[6] AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE OF PSEUDOMONAS-AERUGINOSA - STRUCTURAL REQUIREMENTS OF SUBSTRATE [J].

YAGISAWA, M ;

KONDO, S ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1975, 28 (06) :486-489

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