SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF NEW THIADIAZEPINDIOXIDES

被引：20

作者：

GIANNOTTI, D ^{[1
]}

VITI, G ^{[1
]}

NANNICINI, R ^{[1
]}

PESTELLINI, V ^{[1
]}

BELLAROSA, D ^{[1
]}

机构：

[1] MENARINI SUD,DEPT PHARMACOL RES,POMEZIA,ITALY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 14期

关键词：

D O I：

10.1016/0960-894X(95)00257-T

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

New pyridobenzo-and dipyridothiadiazepindioxides 3-5 and two isomers 13-14 were synthetized and their anti HIV-1 activity and the cytotoxicity were evaluated in vitro. A good antiviral activity was shown by pyridobenzothiadiazepindioxides 4, compound 4a being the best.

引用

页码：1461 / 1466

页数：6

共 20 条

[1]

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[2]

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[3]

BELLAROSA D, 1994, 10TH INT C AIDS YOK, P113

[4]

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