INTERACTION BETWEEN DAUNORUBICIN AND CHROMATIN FROM EHRLICH ASCITES TUMOR-CELLS

被引：17

作者：

SABEUR, G

GENEST, D

AUBELSADRON, G

机构：

[1] Centre de Biophysique Moléculaire

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 88卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)92107-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Interaction of daunorubicin with chromatin from Ehrlich ascites tumor cells has been studied by spectrofluorimetry. Daunorubicin interacts with chromatin and displays at least two types of binding. The number of binding sites is reduced when compared to deoxyribonucleic acid. There is no difference in the overall structure of chromatins extracted from cells sensitive or resistant to daunorubicin. © 1979.

引用

页码：722 / 729

页数：8

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