MAGNETIC-RESONANCE-IMAGING OF HYPERBARIC-OXYGEN TREATED RATS WITH SPINAL-CORD INJURY - PRELIMINARY STUDIES

被引:15
作者
NARAYANA, PA
KUDRLE, WA
LIU, SJ
CHARNOV, JH
BUTLER, BD
HARRIS, JH
机构
[1] Department of Radiology, University of Texas Medical School, Houston
[2] Department of Anesthesiology, University of Texas Medical School, Houston
关键词
MAGNETIC RESONANCE IMAGING; SPINAL CORD INJURY; HYPERBORIC OXYGEN TREATMENT;
D O I
10.1016/0730-725X(91)90431-K
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Magnetic resonance imaging (MRI) has been performed to assess the efficacy of hyperbaric oxygen (HBO) treatment on experimental spinal cord injury in a rat animal model. A moderately severe injury, similar to Type III injury seen in humans (Kulkarni et al. Radiology 164:837; 1987) has been chosen for these studies. An improvement in the neurologic recovery (based on Tarlov scale) has been observed following HBO treatment over a period of 72 hr. Based on MRI, HBO treatment appears to arrest the spread of hemorrhage and resolve edema.
引用
收藏
页码:423 / 428
页数:6
相关论文
共 25 条
[1]  
Kulkarni, McArdle, Kopanicky, Miner, Cotler, Lee, Harris, Acute spinal cord injury: MR imaging at 1.5 T, Radiology, 164, pp. 837-843, (1987)
[2]  
Kulkarni, Bondurant, Rose, Narayana, 1.5 Tesla magnetic resonance imaging of acute spinal trauma, Radiographics, 8, pp. 1059-1082, (1988)
[3]  
Hackney, Asoto, Joseph, Et al., Hemorrhage and edema in acute spinal cord compression: Demonstration by MRI imaging, Radiology, 161, pp. 387-390, (1986)
[4]  
Weirich, Cotler, Narayana, Hazle, Jackson, Coupe, McDonald, Langford, Harris, Histopathologic correlation of magnetic resonance image signal patterns in spinal cord injury model, Spine, 15, pp. 630-638, (1990)
[5]  
Lemaire, Duncan, Solsberg, Armstrong, In vitro magnetic resonance microimaging of the spinal cord, Magn. Reson. Med., 14, pp. 97-104, (1990)
[6]  
Hyperbaric Oxygen Therapy: A Committee Report, (1990)
[7]  
Bassett, Bennett, Introduction to the physical and physiological bases of hyperbaric therapy, Hyperbaric Oxygen Therapy, pp. 11-24, (1977)
[8]  
Nylander, Tissue ischemia and hyperbaric oxygen treatment. An experimental study, Linköping University Medical Dissertations, 231, (1986)
[9]  
Nylander, Lewis, Nordstrom, Larson, Reduction of post-ischemic edema with hyperbaric oxygen, Plast. Reconstr. Surg., 76, pp. 596-601, (1985)
[10]  
Skyhar, Hargens, Strauss, Gershuni, Hart, Akeson, Hyperbaric oxygen reduces edema and necrosis of skeletal muscle in compartment syndromes associated with hemorrhagic hypotension, J. Bone Joint Surg., 68 A, pp. 1218-1224, (1986)