CHELATION CONTROLLED ALDOL REACTION OF TETRONIC ACID DIANION WITH KETONES

被引：7

作者：

HONDA, T

KONDOH, H

OKUYAMA, A

HAYAKAWA, T

TSUBUKI, M

NAGASE, H

机构：

[1] Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo, 142

来源：

HETEROCYCLES | 1992年 / 33卷 / 01期

关键词：

D O I：

10.3987/COM-91-S18

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chelation effect in the aldol reaction of dianion of tetronic acid with ketones was investigated to give the erythro adduct, predominantly, via the six-membered chelation transition state. The carbon-carbon bond formation occurred at the 5-position siteselectively in this reaction.

引用

页码：67 / 72

页数：6

共 8 条

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