ANALYSIS OF MULTICOMPONENT SPECTRA BY THE SIMPLEX-METHOD

被引:7
作者
BLANCO, M [1 ]
CERDA, V [1 ]
COELLO, J [1 ]
GENE, J [1 ]
ITURRIAGA, H [1 ]
MASPOCH, S [1 ]
机构
[1] UNIV ILLES BALEARS,E-07071 PALMA DE MALLORCA,SPAIN
关键词
MULTICOMPONENT ANALYSIS; SIMPLEX METHOD;
D O I
10.1080/00032719208016114
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The Simplex method to simultaneously identify and quantify the components of complex mixtures from their UV-visible spectra is used. Calibration was performed by using a data base containing the spectra of the pure components potentially present. The method for selection of components from the data base was developed on the basis of binary mixtures of dyes and was subsequently applied to the resolution of binary, ternary and quaternary mixtures of active principles in pharmaceutical formulations.
引用
收藏
页码:543 / 560
页数:18
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