AGGREGATION OF SPONGE CELLS - ISOLATION AND CHARACTERIZATION OF AN INHIBITOR OF AGGREGATION RECEPTOR FROM THE CELL-SURFACE

被引：32

作者：

MULLER, WEG

ZAHN, RK

KURELEC, B

MULLER, I

VAITH, P

UHLENBRUCK, G

机构：

[1] RUDJER BOSKOVIC INST, CTR MARINE RES, MARINE MOLEC BIOL LAB, YU-41001 Zagreb, YUGOSLAVIA

[2] UNIV COLOGNE, MED KLIN, D-5000 COLOGNE 41, GERMANY

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1979年 / 97卷 / 02期

关键词：

D O I：

10.1111/j.1432-1033.1979.tb13147.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From the cell membranes of the sponge Geodia cydonium a component was isolated and purified which inhibits the aggregation factor isolated from the same source; the component was termed anti‐aggregation receptor. This molecule was characterized as a glycoprotein (54% neutral carbohydrate) and its molecular weight is in the range of 18000. One biological site of the anti‐aggregation receptor was determined to be d‐galactose. Indirect evidence presented seems to indicate that this molecule is present in an active form in aggregation‐deficient cells and absent in aggregation‐susceptible cells. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：585 / 591

页数：7

共 27 条

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[3]

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DETERMANN H, 1967, GELCHROMATOGRAPHIE