BINDING OF FORMYLMETHIONYL-TRNA AND AMINOACYL-TRNA TO RIBOSOMES

被引:23
作者
OHTA, T
THACH, RE
机构
[1] Department of Chemistry, Harvard University, Cambridge, MA
关键词
D O I
10.1038/219238a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Inhibition of aminoacyl-tRNA binding by the purified initiation factors f1 and f2 could be regarded as a mechanism for ensuring that only F-met-tRNA binds initially to the entry site, thereby preventing random or non-specific binding by aminoacyl-tRNA. This inhibition would be relieved by the hydrolysis of the GTP molecule normally involved in the binding of F-met-tRNA. © 1968 Nature Publishing Group.
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页码:238 / &
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