THE SYNTHESIS OF DIBENZOFURAN BASED DIACIDS AND AMINO-ACIDS DESIGNED TO NUCLEATE PARALLEL AND ANTIPARALLEL BETA-SHEET FORMATION

被引：47

作者：

DIAZ, H ^{[1
]}

KELLY, JW ^{[1
]}

机构：

[1] TEXAS A&M UNIV SYST,DEPT CHEM,COLLEGE STN,TX 77843

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)93540-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-(N-tert-butyloxycarbonyl-2-aminoethyl-)-6-dibenzofuranpropionic acid (1) and 4,6-dibenzofurandipropionic acid (2) designed to nucleate antiparallel and parallel beta-sheet formation, respectively, have been synthesized in multi-gram quantities.

引用

页码：5725 / 5728

页数：4

共 26 条

[1] CHAN TH, 1979, J AM CHEM SOC, P761
[2] CREIGHTON TE, 1984, PROTEINS STRUCTURES, P191
[3] FEIGEL M, 1989, LIEBIGS ANN CHEM, P459
[4] 2,8-DIMETHYL-4-(CARBOXYMETHYL)-6-(AMINOMETHYL)PHENOXATHIIN S-DIOXIDE - AN ORGANIC SUBSTITUTE FOR THE BETA-TURN IN PEPTIDES
FEIGEL, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (01) : 181 - 182
[5] BIOACTIVE CONFORMATION OF LUTEINIZING-HORMONE-RELEASING HORMONE - EVIDENCE FROM A CONFORMATIONALLY CONSTRAINED ANALOG
FREIDINGER, RM
VEBER, DF
PERLOW, DS
BROOKS, JR
SAPERSTEIN, R
[J]. SCIENCE, 1980, 210 (4470) : 656 - 658
[6] STEREOSPECIFIC SYNTHESIS OF A NEW MORPHINE PARTIAL STRUCTURE
HAEFLIGER, W
KLOPPNER, E
[J]. HELVETICA CHIMICA ACTA, 1982, 65 (06) : 1837 - 1852
[7] HECK RF, 1976, J ORG CHEM, V41, P265
[8] HOLZEMANN G, 1991, KONTAKTE DARMSTADT, P3
[9] THE DESIGN AND SYNTHESIS OF A NONPEPTIDE MIMIC OF AN IMMUNOSUPPRESSING PEPTIDE
KAHN, M
DEVENS, B
[J]. TETRAHEDRON LETTERS, 1986, 27 (40) : 4841 - 4844
[10] THE INCORPORATION OF BETA-TURN PROSTHETIC UNITS INTO MERRIFIELD SOLID-PHASE PEPTIDE-SYNTHESIS
KAHN, M
BERTENSHAW, S
[J]. TETRAHEDRON LETTERS, 1989, 30 (18) : 2317 - 2320

← 1 2 3 →