DIAGNOSTIC SPECIFICITY OF IMMUNOGLOBULIN-M (IGM) RESPONSE IN DIFFERENTIATING LEGIONNAIRES DISEASE FROM PSITTACOSIS

被引：13

作者：

LATTIMER, GL

ORMSBEE, RA

PEACOCK, MG

RHODES, LV

机构：

[1] ALLENTOWN SACRED HEART HOSP,ALLENTOWN,PA

[2] ALLENTOWN GEN HOSP,ALLENTOWN,PA

[3] NIAID,ROCKY MOUNTAIN LAB,HAMILTON,MT 59840

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 1979年 / 11卷 / 04期

关键词：

D O I：

10.3109/inf.1979.11.issue-4.03

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Specific IgM and IgG antibody responses to Legionella pneumophila (LDB) and Chlamydia psittaci (PSI) in serum specimens from 22 cases of Legionnaires’ Disease (LD) were examined by micro-immunofluorescence (IF) tests to explore the diagnostic significance of the IgM antibody response. Serial samples from 5 patients with LD showed 4-fold changes in IgG antibody against LDB and PSI. All 5 patients possessed IgM antibodies against LDB but not against PSI. In single convalescent serum samples from 17 additional cases, 16 exhibited IgG and 15 showed IgM antibodies against LDB; all 17 exhibited IgG but not IgM antibodies against PSI. The IgM antibody response appears more specific than the corresponding IgG response in the serodiagnosis of LD, and may be valuable in differentiating LDB infections from those due to PSI. © 1979, Informa UK Ltd. All rights reserved.

引用

页码：271 / 273

页数：3

共 8 条

[1] BOCK BV, 1978, LANCET, V1, P410
[2] LEGIONNAIRES DISEASE - CLINICAL FINDINGS AND ONE-YEAR FOLLOW-UP
LATTIMER, GL
RHODES, LV
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1978, 240 (11): : 1169 - 1171
[3] LEGIONNAIRES DISEASE - ISOLATION OF A BACTERIUM AND DEMONSTRATION OF ITS ROLE IN OTHER RESPIRATORY-DISEASE
MCDADE, JE
SHEPARD, CC
FRASER, DW
TSAI, TR
REDUS, MA
DOWDLE, WR
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (22) : 1197 - 1203
[4] MIMS CA, 1976, PATHOGENESIS INFECTI, P98
[5] LEGIONNAIRES DISEASE - ANTIGENIC PECULIARITIES, STRAIN DIFFERENCES, AND ANTIBIOTIC SENSITIVITIES OF AGENT
ORMSBEE, RA
PEACOCK, MG
LATTIMER, GL
PAGE, LA
FISET, P
[J]. JOURNAL OF INFECTIOUS DISEASES, 1978, 138 (02) : 260 - 264
[6] FALSE POSITIVE REACTIONS IN THE INDIRECT FLUORESCENT-ANTIBODY TEST FOR LEGIONNAIRES DISEASE ELIMINATED BY USE OF FORMOLIZED YOLK-SAC ANTIGEN
TAYLOR, AG
HARRISON, TG
DIGHERO, MW
BRADSTREET, CMP
[J]. ANNALS OF INTERNAL MEDICINE, 1979, 90 (04) : 686 - 689
[7] DIAGNOSIS OF LEGIONNAIRES DISEASE
TSAI, TF
FRASER, DW
[J]. ANNALS OF INTERNAL MEDICINE, 1978, 89 (03) : 413 - 414
[8] 1976, MORBIDITY MORTALITY, V25, P270

← 1 →