A COMPARATIVE-STUDY ON TISSUE DISTRIBUTION AND METABOLIC ADAPTATION OF IMP-GMP 5'-NUCLEOTIDASE

被引：32

作者：

ITOH, R

ECHIZEN, H

HIGUCHI, M

OKA, J

YAMADA, K

机构：

[1] The National Institute of Health and Nutrition, Shinjuku-ku, Tokyo

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 103卷 / 01期

关键词：

D O I：

10.1016/0305-0491(92)90427-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Activity of a cytoplasmic 5'-nucleotidase which preferentially hydrolyzes IMP and GMP (IMP GMP 5'-nucleotidase) was determined by a specific immunochemical method in two species of birds and two species of mammals. 2. The activity was markedly high in avian liver, and it increased two-fold in response to a high protein diet in chicken liver. 3. In mammals, the activity was high in testis and spleen. In the rat, the activities in liver, kidney and heart extracts increased by about 30% in response to the high protein diet, while they increased three-fold in regenerating liver. 4. Low activities were detected in skeletal muscles and in erythrocytes of all the species studied.

引用

页码：153 / 159

页数：7

共 25 条

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