DYNAMICAL ORDER AND DISORDER IN LIPID BILAYERS

被引：254

作者：

MOURITSEN, OG

JORGENSEN, K

机构：

[1] Department of Physical Chemistry, The Technical University of Denmark, DK-2800 Lyngby

来源：

CHEMISTRY AND PHYSICS OF LIPIDS | 1994年 / 73卷 / 1-2期

关键词：

PHOSPHOLIPIDS; PHASE TRANSITION; PHASE-SEPARATION DYNAMICS; LOCAL ORDER; DYNAMIC HETEROGENEITY; LIPID DOMAINS; CHOLESTEROL; DRUGS;

D O I：

10.1016/0009-3084(94)90171-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Various order and disorder phenomena in lipid bilayers are considered as they arise due to the very many-particle character of the bilayer. Particular attention is paid to dynamically maintained order in terms of lateral density- and compositional fluctuations that lead to dynamic heterogeneity, local structure, and lipid-domain formation on length scales of 10-1000 Angstrom. The influence of cholesterol and various drugs on the local structure is described. A discussion is presented of the possible role played by lipid order and disorder phenomena for the functional dynamics of membranes.

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页码：3 / 25

页数：23

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