CYSTIC-FIBROSIS - A NEW CHALLENGE FOR CARDIOTHORACIC SURGERY

被引：10

作者：

FRADET, G ^{[1
]}

SMYTH, RL ^{[1
]}

SCOTT, JP ^{[1
]}

SOLIS, E ^{[1
]}

SHARPLES, L ^{[1
]}

HIGENBOTTAM, TW ^{[1
]}

WALLWORK, J ^{[1
]}

机构：

[1] PAPWORTH HOSP,DEPT TRANSPLANTAT SURG,CAMBRIDGE CB3 8RE,ENGLAND

来源：

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | 1990年 / 4卷 / 03期

关键词：

Cystic fibrosis; Infection; Rejection; Transplantation;

D O I：

10.1016/1010-7940(90)90184-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cystic fibrosis (CF) is the most common fatal inherited disease incaucasian populations. Between 80-120 CF patients die each year in Englandand Wales, the majority from pulmonary disease. Since October 1985, 17patients with CF have undergone heart-lung transplantation (HLT) at ourinstitution. Only 3 early deaths have occurred in the first 2 postoperativemonths. Another patient died 9 months after transplantation. Thirteenpatients are now alive 1-46 months (mean 14 month) post transplantation.Actuarial survival at 6 months is 80% for CF patients compared to 73% fornon-CF patients. Both groups of patients have similar profiles of rejectionand infection. In the Caucasian population, CF patients form the largestpotential recipient group for HLT and our experience suggests that those CFpatients who undergo HLT have a favourable outcome. © Springer-Verlag.

引用

页码：136 / 141

页数：6

共 18 条

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