ENZYMATIC CHANGES IN GUINEA-PIG LUNGS DUE TO HEMATITE DUST

被引:1
作者
JAISWAL, AK
RAHMAN, Q
VISWANATHAN, PN
机构
[1] Industrial Toxicology Research Centre, Lucknow, 226001, Post Box No. 80, Mahatma Gandhi Marg
关键词
D O I
10.1016/0378-4274(79)90106-1
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
The changes in activities of glucose-6-phosphate dehydrogenase, fructose diphosphatase, adenyl cyclase, succinic dehydrogenase and carbonic anhydrase were followed in guinea pig lungs at 50,100 and 150 days after an intratracheal injection of 50 mg haematite dust. Fructose diphosphatase was elevated and adenyl cyclase unaffected, while the other activities decreased. The significance of these findings in relation to inhaled iron ore toxicity is discussed. © 1979.
引用
收藏
页码:51 / 54
页数:4
相关论文
共 14 条
[1]  
HUNTER D, 1969, DISEASES OCCUPATIONS, P944
[2]  
JAISWAL AK, 1978, IND HLTH JAPAN, V15, P117
[3]   GLUCOSE-6-PHOSPHATE DEHYDROGENASE - 6-PHOSPHOGLUCONIC DEHYDROGENASE [J].
KORNBERG, A ;
HORECKER, BL ;
SMYRNIOTIS, PZ .
METHODS IN ENZYMOLOGY, 1955, 1 :323-327
[4]  
LOWRY OH, 1951, J BIOL CHEM, V193, P265
[5]   BIOCHEMICAL CHANGES IN GUINEA-PIG LUNGS DUE TO AMOSITE ASBESTOS [J].
MISRA, V ;
RAHMAN, Q ;
VISWANATHAN, PN .
ENVIRONMENTAL RESEARCH, 1978, 16 (1-3) :55-61
[6]  
POGELL BM, 1952, J BIOL CHEM, V197, P293
[7]   SOME NEW PERSPECTIVES ON BIOLOGICAL EFFECTS OF ASBESTOS [J].
RAHMAN, Q ;
VISWANATHAN, PN ;
ZAIDI, SH .
ENVIRONMENTAL RESEARCH, 1977, 14 (03) :487-498
[8]  
RAHMAN Q, 1976, TOXICOL APPL PHARMAC, V38, P472
[9]  
ROUGHTON RJW, 1946, BIOCHEM J, V40, P309
[10]   AMINO-ACID CHANGES AND PULMONARY RESPONSE OF RATS TO SILICA DUST [J].
SINGH, J ;
KAW, JL ;
PANDEY, SD ;
VISWANATHAN, PN ;
ZAIDI, SH .
ENVIRONMENTAL RESEARCH, 1977, 14 (03) :452-462