MECHANISM OF HYPERLIPEMIA IN THE NEPHROTIC SYNDROME

被引：9

作者：

DIXIT, VM

HETTIARATCHI, ESG

机构：

[1] Department of Medical Physiology, University of Nairobi, Nairobi

来源：

MEDICAL HYPOTHESES | 1979年 / 5卷 / 12期

关键词：

HDL; Hypercholesteremia; Hyperlipidaemia; Hypoproteinemia; Lipoprotein lipase; Lipoproteins; Nephrosis lipoid; Nephrotic syndrome;

D O I：

10.1016/0306-9877(79)90102-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The mechanism of hyperlipidaemia in the nephrotic syndrome has not been fully established. We propose that it results from hypoalbuminaemia due to inhibition of the reaction catalysed by lecithin cholesterol acyltransferase converting cholesterol of high density lipoproteins to cholesterol esters and to an inhibition of high density lipoprotein particle formation from very low density lipoproteins due to reduced activity of lipoprotein lipase. © 1979.

引用

页码：1327 / 1331

页数：5

共 27 条

[1]

ALLEN LC, 1961, J CLIN INVEST, V40, P499

[2] HYPERLIPOPROTEINEMIA IN NEPHROSIS [J].