CHIRAL CYCLOBUTANONES AS VERSATILE SYNTHONS - THE 1ST ENANTIOSELECTIVE TOTAL SYNTHESIS OF (+)-LAURENE

被引：46

作者：

NEMOTO, H ^{[1
]}

NAGAMOCHI, M ^{[1
]}

FUKUMOTO, K ^{[1
]}

机构：

[1] TOHOKU UNIV,INST PHARMACEUT,SENDAI,MIYAGI 980,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 19期

关键词：

D O I：

10.1039/p19930002329

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and convenient route to the thermodynamically unstable ketone 11 via the cyclopentanone 8 which was synthesised by palladium-mediated ring expansion of the chiral siloxyvinylcyclobutanes 9 and 10 has been developed. This leads to an enantioselective total synthesis of (+)-laurene 1.

引用

页码：2329 / 2332

页数：4

共 29 条

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