学术探索
学术期刊
新闻热点
数据分析
智能评审

PERIPHERAL NEUROPATHY IN MUTANT DIABETIC MOUSE [C57BL-KS(DB-DB)]

被引：93
作者：
SIMA, AAF
ROBERTSON, DM
机构：
[1] QUEENS UNIV, DEPT PATHOL, KINGSTON K7L 3N6, ONTARIO, CANADA
[2] KINGSTON GEN HOSP, KINGSTON K7L 3N6, ONTARIO, CANADA
来源：
ACTA NEUROPATHOLOGICA | 1978年 / 41卷 / 02期
关键词：
Diabetic neuropathy; Morphology; Morphometry; Motor nerve conduction velocity;
D O I：
10.1007/BF00689757
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A new animal model for the study of diabetic neuropathy is presented. The homozygote (db/db) of the mouse strain C57BL/Ks shows severe diabetes with longstanding hyperglycemia. Electrophysiological studies showed severely decreased motor nerve conduction velocity. Morphometric examination of sensory and motor nerves at different levels revealed absence of large myelinated fibers, with morphological features indicative of axonal atrophy. © 1978 Springer-Verlag.
引用
收藏
页码：85 / 89
页数：5
相关论文
共 30 条
123