CYCLOPROPANO-STEROIDS

被引：14

作者：

EVANS, DE

LEWIS, GS

PALMER, PJ

WEYELL, DJ

机构：

[1] Research Laboratories, Parke Davis and Company, Hounslow, Middx., Staines Road

[2] Twyford Laboratories Ltd., London N.W.10

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1968年 / 10期

关键词：

D O I：

10.1039/j39680001197

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The modified Wolff-Kishner reduction of 2-methylene- and substituted 2-methylene-Δ4-3-oxo-steroids in the 19-methyl and 19-nor series has been used to prepare 2α,3α-cyclopropano-steroids. The products obtained have been correlated with those resulting from the reaction of 1 α-hydroxy-2-enes with methylene iodide/zinc-copper complex and of 1-oxo-2-enes with dimethylsulphoxonium methylide. The latter reagent has also been used to prepare some spirocyclopropano-steroids.

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页码：1197 / &

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