THE RISKS OF EARLY CORDOCENTESIS (12-21 WEEKS) - ANALYSIS OF 500 PROCEDURES

被引：46

作者：

ORLANDI, F ^{[1
]}

DAMIANI, G ^{[1
]}

JAKIL, C ^{[1
]}

LAURICELLA, S ^{[1
]}

BERTOLINO, O ^{[1
]}

MAGGIO, A ^{[1
]}

机构：

[1] OSPED V CERVELLO,SERV DIAGNOSI & CURA TALASSEMIA,PALERMO,ITALY

来源：

PRENATAL DIAGNOSIS | 1990年 / 10卷 / 07期

关键词：

Cordocentesis; Fetal blood; Fetal karyotype; Prenatal diagnosis; Thalassaemia;

D O I：

10.1002/pd.1970100703

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Five hundred cordocenteses were performed between 12 and 21 weeks. The indications were thalassaemia (386), rapid karyotyping (97), feto‐maternal allo‐immunization (10), rubella (6), and toxoplasmosis (1). One hundred and ten pregnancies underwent termination on the basis of the result, while 20 of the 370 pregnancies intended to continue were lost to follow‐up. Amongst these were 16 fetal losses (4·3 per cent) and 22 premature deliveries (5·9 per cent); no other complications were reported. Four adverse prognostic factors were identified: (a) cord bleeding; (b) fetal bradycardia; (c) prolonged procedure time; and (d) anterior insertion of the placenta. There was no‘obvious’ difference in fetal loss rate with advancing gestation until 19–21 weeks, when the risk of fetal loss decreased to 2·5 per cent. Copyright © 1990 John Wiley & Sons, Ltd.

引用

页码：425 / 428

页数：4

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